Trade-Offs of Evolution Involved in Senescence

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Supertopics:

Trade-Offs in Natural Selection
Why Organisms Age and Die (Senescence)

Trade-Offs of Evolution Involved in Senescence

Subtopics:

The Mechanistic Target of Rapamycin (mTOR)
Exploiting mTOR to Slow Aging
a leucine-mediated threshold in mTOR signalling	web	Xiangyu Zhang, Divya Kapoor	Nature Metabolism	2024-02-19
mTOR at the nexus of nutrition, growth, aging and disease	web	Grace Y Liu, David M Sabatini	Nat Rev Mol Cell Biol	2021-04-01
twenty-five years of mTOR (from nutrients to growth)	web	David M Sabatini	Proc Natl Acad Sci	2017-11-07
aging is simply the continuation of developmental growth	web	Blagosklonny MV	Cell Cycle	2013-11-15
acne linked with overactivated mTORC signaling	web	Melnik BC, John SM	Acta Derm Venereol	2013-11-01
fisetin regulates obesity by targeting mTORC1	web	Jung CH, Kim H, Ahn J	J Nutr Biochem	2013-03-18
milk activates mTORC signaling for postnatal growth	web	Melnik BC, John SM	Nutr J	2013-07-25
mTORC activity as a determinant of cancer risk	web	McCarty MF	Med Hypotheses	2011-10-01
mTOR triggers growth then later cancer and aging	web	Zoncu R, Efeyan A	Nat Rev Mol Cell Biol	2010-12-15
TOR-driven aging is like a speeding car without breaks	web	Blagosklonny MV	Cell Cycle	2009-12-09
The Pleiotropic Theory of Senescence
antagonistic pleiotropy hypothesis in wikipedia	web		Wikipedia	2012-05-25
problems with the antagonistic pleiotropy theory	web		Programmed Aging Theory Info	2009-01-01
Williams' Paper on Pleiotropic Senescence