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antibiotic manikomycin found in soil works differently
a depsipeptide antibiotic binds the E-site of the ribosome
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https://www.nature.com/articles/s41586-026-10589-2#Sec7:~:text=The%20resistance%20frequencies%20for%20wild%2Dtype%20strains%20were%20as%20low%20as%203.7%E2%80%89%C3%97%E2%80%8910%E2%88%9210%20for%20E.%20coli%20BW25113%20and%201.1%E2%80%89%C3%97%E2%80%8910%E2%88%928%20for%20Klebsiella%20pneumoniae%C2%A0C1559.
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